Henryk Łowmiański (1898-1984)

C1py00484k 1890..1898

End-functionalized polyethylene oxides containing cleavable acetal and clickable azide terminal groups (PEO-acetal-N3 and N3-acetal-PEO-acetal-N3) were obtained by the reaction between commercially available PEOs and 2-chloroethyl vinyl ether using pyridinium p-toluenesulfonate. This results in acetal-linkages which can be further functionalized by nucleophilic displacement with sodium azide. B...

Hilde Mangold-Pröscholdt (1898 – 1924)

In the history of medicine, few women were awarded an eponym. One can assume that this doesn’t have anything to do with their second X-chromosome or the weight of their brains. Most probably, it was the era that was not on their side. In the time period wherein most eponyms were given, women had almost no access to higher education. There are a few exceptions of course, such as Marie Curie or V...

Henryk M. Wisniewski and the amyloid theory of Alzheimer's disease.

The amyloid theory of Alzheimer’s disease (AD) is now the dominant paradigm for the etiology of this particular neurodegenerative disorder, and Henryk Wisniewski played a major role in its elaboration. Together with Robert Terry, in the early 1970’s, they were in a position to take advantage of the electron microscope to give a fine structural account of the appearances of Aβ amyloid deposition...

Helen B. Taussig (1898-1986)

Together with Alfred Blalock, Helen Taussig rose to fame because of the Blalock-Taussig shunt. This is a surgical procedure in children who suffer from hypoxia because of a congenital cardiac malformation. Because of this affliction, they are blue. Less known is the fact that dr. Taussig also played a crucial role in the prohibition of thalidomide in the USA, the drug that had been responsible ...

Lionel Sharples Penrose (1898-1972).